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2013年獲浙江大學博士學位;2013—2016年擔任浙江大學求是高等研究院講師;2016—2021年在美國耶魯大學醫(yī)學院從事博士后研究, 獲Rudolph J Anderson fellowship和CRI Irvington Postdoctoral fellowship資助; 2021年1月起擔任中科院分子細胞科學卓越創(chuàng)新中心(生化與細胞所)研究員、研究組長、博士生導師。

　　在腫瘤發(fā)展和轉(zhuǎn)移過程中，腫瘤細胞通過基因突變塑造的微環(huán)境是其逃逸免疫監(jiān)視和免疫治療的關(guān)鍵。利用CRISPR基因編輯和高通量篩選技術(shù)剖析腫瘤微環(huán)境中，對于腫瘤免疫逃逸和免疫治療應答具有關(guān)鍵調(diào)控作用的免疫細胞亞群和分子，旨在發(fā)現(xiàn)新的免疫治療靶標。研究組還將進一步探索如何將上述免疫治療靶標與T細胞療法或溶瘤病毒療法結(jié)合起來，開發(fā)新型免疫療法。

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